Background: In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan\u2019s elimination status.<\/p>\n
Methods: A nationwide, three-stage, cluster seroprevalence survey was conducted among individuals aged 1\u20134, 5\u201317, and >20 years in 2017. Demographic information and children\u2019s vaccination history were collected, and a blood specimen was drawn. Serum was tested for measles and rubella immunoglobulin G (IgG). Frequencies, weighted proportions, and prevalence ratios for measles and rubella seropositivity were calculated by demographic and vaccination history, taking into account the study design.<\/p>\n
Results: Of the 1325 individuals tested, 1045 (81%, 95% CI 78%\u201385%) were measles IgG seropositive, and 1290 (97%, 95% CI 95%\u201399%) were rubella IgG seropositive. Rubella IgG seropositivity was high in all three age strata, but only 47% of those aged 5\u201317 years were measles IgG seropositive. Additionally, only 41% of those aged 5\u201317 years who had documented receipt of two doses of measles\u2013 or measles-rubella\u2013containing vaccine were seropositive for measles IgG, but almost all these children were rubella IgG seropositive.<\/p>\n
Conclusions: An unexpected measles immunity gap was identified among children 5\u201317 years of age. It is unclear why this immunity gap exists; however, it could have led to a large outbreak and threatened sustaining of measles elimination in Bhutan. Based on this finding, a mass vaccination campaign was conducted to close the immunity gap. Background: In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan\u2019s elimination status. Methods: A nationwide, three-stage, cluster seroprevalence survey was conducted among…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[41],"class_list":["post-2412","post","type-post","status-publish","format-standard","hentry","category-publication","tag-research-paper","category-16","description-off"],"_links":{"self":[{"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=\/wp\/v2\/posts\/2412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2412"}],"version-history":[{"count":0,"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=\/wp\/v2\/posts\/2412\/revisions"}],"wp:attachment":[{"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2412"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2412"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rcdc.indevconsultancy.in\/web\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nBhutan Measles Rubella Serosurvey<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"